- Abstract:
-
This thesis investigates antigenic variation and its evolution in Plasmodium falciparum, the cause of the most deadly form of human malaria. Antigenic variation is a strategy for evading immunity by switching between antigenic variants during infection. In P. falciparum, such variable antigens confer different binding phenotypes that may affect parasite survival and have also been linked to pathology. Here, a new statistical method is described for determining the switching patterns that u...
Expand abstract - Funding agency for:
- Robert Noble
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- URN:
-
uuid:271b8ef9-4e14-42e3-80e6-5584119e20ca
- Local pid:
- ora:8295
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Robert Noble
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
Thesis
Antigenic variation and its evolution in P. falciparum malaria
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+ Biotechnology and Biological Sciences Research Council
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