Journal article
Cellular penetration and nuclear importation properties of 111In-labeled and 123I-labeled HIV-1 tat peptide immunoconjugates in BT-474 human breast cancer cells.
- Abstract:
-
INTRODUCTION: Our objective was to compare the cell penetration and nuclear importation properties of 111In-labeled and 123I-labeled immunoconjugates (ICs) composed of 16-mer peptides (GRKKRRQRRRPPQGYG) derived from HIV-1 transactivator of transcription (tat) protein and anti-mouse IgG (mIgG) in BT-474 breast cancer (BC) cells. METHODS: [111In]tat ICs were constructed by site-specific conjugation of tat peptides to NaIO4(-)-oxidized carbohydrates in the Fc domain of diethylenetriaminepentaac...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.nucmedbio.2006.10.008
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Bibliographic Details
- Journal:
- Nuclear medicine and biology
- Volume:
- 34
- Issue:
- 1
- Pages:
- 37-46
- Publication date:
- 2007-01-01
- DOI:
- EISSN:
-
1872-9614
- ISSN:
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0969-8051
- Source identifiers:
-
257729
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:257729
- UUID:
-
uuid:26fa28e3-d2d2-4522-beb2-e507ea6d55bb
- Local pid:
- pubs:257729
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2007
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