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Further radiobiologic modeling of palliative radiotherapy: use of virtual trials.

Abstract:

PURPOSE: To study duration of response in palliative radiotherapy in a population of tumors. METHODS AND MATERIALS: Models of dynamic changes in cell number with time were used to develop a function for the remission time (T(rem)) after palliative radiotherapy: [See Equation], where BED is the biologically effective dose, t(1) the duration of symptoms (i.e., the time between the onset of symptoms and the initiation of radiotherapy), K the daily BED repopulation equivalent, alpha the linear r...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Journal:
International journal of radiation oncology, biology, physics
Volume:
69
Issue:
1
Pages:
221-229
Publication date:
2007-09-05
DOI:
EISSN:
1879-355X
ISSN:
0360-3016
URN:
uuid:26e2fbd3-1e46-48b3-a21b-fb5f44b44ea5
Source identifiers:
312518
Local pid:
pubs:312518

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