Journal article
THEMIS: Two models, different thresholds.
- Abstract:
-
THEMIS, a recently identified T-lineage-restricted protein, is the founding member of a large metazoan protein family. Gene inactivation studies have revealed a critical requirement for THEMIS during thymocyte positive selection, implicating THEMIS in signaling downstream of the T cell antigen receptor (TCR), but the mechanistic underpinnings of THEMIS function have remained elusive. A previous model posited that THEMIS prevents thymocytes from inappropriately crossing the positive/negative s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.it.2017.06.006
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Authors
Funding
French National Institute of Health and Medical Research
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Medical Research Council
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Trends in Immunology Journal website
- Publication date:
- 2017-07-01
- DOI:
- EISSN:
-
1471-4981
- ISSN:
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1471-4906
- Pmid:
-
28697966
- Source identifiers:
-
708009
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:708009
- UUID:
-
uuid:26dc6d21-3c12-4ad1-a6f6-a71a86396c30
- Local pid:
- pubs:708009
- Deposit date:
- 2017-08-21
Terms of use
- Copyright date:
- 2017
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