Journal article icon

Journal article

A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis.

Abstract:

The bone marrow contains specific microenvironmental stem cell niches that maintain haemopoiesis. CXCL12-expressing mesenchymal stromal cells are closely associated with the bone marrow sinusoidal endothelia, forming key elements of the haemopoietic stem cell niche, yet their ability to regulate endothelial function is not clearly defined. Given that the murine nestin(+) cell line, MS-5, provides a clonal surrogate bone marrow stromal niche capable of regulating both murine and human primiti...

Expand abstract

Actions


Access Document


Authors


Tsaknakis, G More by this author
Coldwell, KE More by this author
Roubelakis, MG More by this author
Expand authors...
Journal:
British journal of haematology
Volume:
157
Issue:
3
Pages:
299-311
Publication date:
2012-05-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:26d53f53-d671-48d4-b25f-acc26e889195
Source identifiers:
342014
Local pid:
pubs:342014

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP