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Journal article

The functions of microparticles in pre-eclampsia.

Abstract:

Pre-eclampsia (P-EC), a heterogenic multisystem disorder characterized by hypertension and proteinuria, usually develops in the second half of pregnancy. The incidence is 2 to 5%, and P-EC is therefore a major cause of maternal and perinatal morbidity and mortality. Although the exact etiology is unknown, placental factors released into the maternal circulation lead to systemic maternal inflammation and endothelial dysfunction. Growing evidence indicates that placenta-derived microparticles, ...

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Publication status:
Published

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Publisher copy:
10.1055/s-0030-1270342

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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
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Journal:
Seminars in thrombosis and hemostasis
Volume:
37
Issue:
2
Pages:
146-152
Publication date:
2011-03-05
DOI:
EISSN:
1098-9064
ISSN:
0094-6176
URN:
uuid:26c9c377-f03d-4cfa-9d1b-f565d0b6d4eb
Source identifiers:
248370
Local pid:
pubs:248370

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