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Epigenetic Control of Human Endogenous Retrovirus Expression: focus on regulation of long-terminal repeats (LTRs)

Abstract:

Transposable elements, including endogenous retroviruses (ERVs), comprise almost 45% of the human genome. This could represent a significant pathogenic burden but it is becoming more evident that many of these elements have a positive contribution to make to normal human physiology. In particular, the contributions of human ERVs (HERVs) to gene regulation and the expression of noncoding RNAs has been revealed with the help of new and emerging genomic technologies. HERVs have the common provir...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3390/v9060130

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Magiorkinis, G More by this author
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Funding agency for:
Magiorkinis, G
Publisher:
MDPI Publisher's website
Journal:
Viruses Journal website
Volume:
9
Issue:
6
Pages:
130
Publication date:
2017-05-31
Acceptance date:
2017-05-22
DOI:
EISSN:
1999-4915
ISSN:
1999-4915
Pubs id:
pubs:696727
URN:
uri:26bd276c-175f-4908-9875-17d6bf81bb08
UUID:
uuid:26bd276c-175f-4908-9875-17d6bf81bb08
Local pid:
pubs:696727

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