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Identifying prognostic factors of severe metabolic acidosis and uraemia in African children with severe falciparum malaria: a secondary analysis of a randomized trial

Abstract:

Background
Severe metabolic acidosis and acute kidney injury are major causes of mortality in children with severe malaria but are often underdiagnosed in low resource settings.
Methods
A retrospective analysis of the ‘Artesunate versus quinine in the treatment of severe falciparum malaria in African children’ (AQUAMAT) trial was conducted to identify clinical features of severe metabolic acidosis and uraemia in 5425 children from nine Africa... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12936-021-03785-0

Authors


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Role:
Author
ORCID:
0000-0001-8132-1620
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-5190-2395
Publisher:
BioMed Central
Journal:
Malaria Journal More from this journal
Volume:
20
Issue:
1
Article number:
282
Publication date:
2021-06-25
Acceptance date:
2021-05-27
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Pmid:
34172046
Language:
English
Keywords:
Pubs id:
1183994
Local pid:
pubs:1183994
Deposit date:
2021-07-09

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