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Dictyostelium as a model to assess site-specific ADP-ribosylation events

Abstract:

The amoeba Dictyostelium discoideum is a single-cell organism that can undergo a simple developmental program, making it an excellent model to study the molecular mechanisms of cell motility, signal transduction, and cell-type differentiation. A variety of human genes that are absent or show limited conservation in other invertebrate models have been identified in this organism. This includes ADP-ribosyltransferases, also known as poly-ADP-ribose polymerases (PARPs), a family of proteins that...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/978-1-4939-8588-3_9

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
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Funding agency for:
Rakhimova, A
Publisher:
Springer Verlag Publisher's website
Journal:
Methods in Molecular Biology Journal website
Volume:
1813
Pages:
125-148
Publication date:
2018-08-11
DOI:
ISSN:
1064-3745 and 1940-6029
Pmid:
30097865
Language:
English
Keywords:
Pubs id:
pubs:909911
UUID:
uuid:26a42e5f-a106-47c6-847c-289e0e3ec103
Local pid:
pubs:909911
Deposit date:
2018-11-13

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