Journal article icon

Journal article

The risk of developing cancer following metal-on-metal hip replacement compared with non metal-on-metal hip bearings: Findings from a prospective national registry "The National Joint Registry of England, Wales, Northern Ireland and the Isle of Man"

Abstract:

Background and purpose

Over 1 million metal-on-metal hip replacements were implanted. Even well-functioning implants produce wear debris that can cause tissue damage, disseminate and cause DNA damage. We aimed to establish if there was an association between metal-on-metal hip replacement and the risk of subsequently developing cancer compared with alternative hip replacements.

Methods

We performed a population based prospective longitudinal cohort study using dat...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0204356

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0003-2436-9024
National Institute for Health Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
13
Issue:
9
Pages:
e0204356
Publication date:
2018-09-20
Acceptance date:
2018-09-06
DOI:
EISSN:
1932-6203
Pubs id:
pubs:920817
URN:
uri:265a784f-8ec9-4a89-aa23-bf7d47158469
UUID:
uuid:265a784f-8ec9-4a89-aa23-bf7d47158469
Local pid:
pubs:920817
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP