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Journal article

Identification of the target self-antigens in reperfusion injury.

Abstract:

Reperfusion injury (RI), a potential life-threatening disorder, represents an acute inflammatory response after periods of ischemia resulting from myocardial infarction, stroke, surgery, or trauma. The recent identification of a monoclonal natural IgM that initiates RI led to the identification of nonmuscle myosin heavy chain type II A and C as the self-targets in two different tissues. These results identify a novel pathway in which the innate response to a highly conserved self-antigen expr...

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Publication status:
Published

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Publisher copy:
10.1084/jem.20050390

Authors


Alicot, EM More by this author
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Journal:
The Journal of experimental medicine
Volume:
203
Issue:
1
Pages:
141-152
Publication date:
2006-01-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:26340777-4ce4-4aa6-96f7-17745e96d9b2
Source identifiers:
19487
Local pid:
pubs:19487

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