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The nature of tremor circuits in parkinsonian and essential tremor.

Abstract:

Tremor is a cardinal feature of Parkinson's disease and essential tremor, the two most common movement disorders. Yet, the mechanisms underlying tremor generation remain largely unknown. We hypothesized that driving deep brain stimulation electrodes at a frequency closely matching the patient's own tremor frequency should interact with neural activity responsible for tremor, and that the effect of stimulation on tremor should reveal the role of different deep brain stimulation targets in trem...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awu250

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Molecular Medicine
Foltynie, T More by this author
Limousin, P More by this author
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Publisher:
Oxford University Press
Journal:
Brain : a journal of neurology
Volume:
137
Issue:
Pt 12
Pages:
3223-3234
Publication date:
2014-12-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:263373d3-4308-4c23-8e80-d6490a338cef
Source identifiers:
483826
Local pid:
pubs:483826

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