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The nature of tremor circuits in parkinsonian and essential tremor.

Abstract:

Tremor is a cardinal feature of Parkinson's disease and essential tremor, the two most common movement disorders. Yet, the mechanisms underlying tremor generation remain largely unknown. We hypothesized that driving deep brain stimulation electrodes at a frequency closely matching the patient's own tremor frequency should interact with neural activity responsible for tremor, and that the effect of stimulation on tremor should reveal the role of different deep brain stimulation targets in trem...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awu250

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Publisher:
Oxford University Press
Journal:
Brain : a journal of neurology
Volume:
137
Issue:
Pt 12
Pages:
3223-3234
Publication date:
2014-12-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Source identifiers:
483826
Language:
English
Keywords:
Pubs id:
pubs:483826
UUID:
uuid:263373d3-4308-4c23-8e80-d6490a338cef
Local pid:
pubs:483826
Deposit date:
2014-09-18

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