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Microvascular responsiveness in obesity: implications for therapeutic intervention.

Abstract:

Obesity has detrimental effects on the microcirculation. Functional changes in microvascular responsiveness may increase the risk of developing cardiovascular complications in obese patients. Emerging evidence indicates that selective therapeutic targeting of the microvessels may prevent life-threatening obesity-related vascular complications, such as ischaemic heart disease, heart failure and hypertension. It is also plausible that alterations in adipose tissue microcirculation contribute to...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
Journal:
British journal of pharmacology
Volume:
165
Issue:
3
Pages:
544-560
Publication date:
2012-02-05
DOI:
EISSN:
1476-5381
ISSN:
0007-1188
URN:
uuid:2620225f-e9bf-4a1b-a906-5d16bb7d6b4a
Source identifiers:
167769
Local pid:
pubs:167769

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