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Development of the isolated dual perfused rat liver model as an improved reperfusion model for transplantation research.

Abstract:

The Isolated Perfused Liver (IPL) model is a widely used and appreciated in vitro method to demonstrate liver viability and metabolism. Reperfusion is performed in a controlled setting, however, via the portal vein only. To study transplant related questions concerning bile and transport of bile, the in vitro Isolated dual Perfused Liver model is revisited. The IdPL is an in vitro reperfusion model, using both portal vein and hepatic artery. Livers from 12 Wistar rats were flushed with Univer...

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Publication status:
Published

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Journal:
International journal of artificial organs
Volume:
29
Issue:
2
Pages:
219-227
Publication date:
2006-02-01
EISSN:
1724-6040
ISSN:
0391-3988
Source identifiers:
190972

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