Journal article
Hypoxia upregulates angiogenesis and synovial cell migration in rheumatoid arthritis.
- Abstract:
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INTRODUCTION: Rheumatoid arthritis (RA) is characterised by invasion of cartilage, bone and tendon by inflamed synovium. Previous studies in our laboratory have shown that hypoxia is a feature of RA synovitis. In the present study, we investigated the consequences of hypoxia on angiogenesis and synovial fibroblast migration in RA. METHODS: Synovial tissue was harvested from RA patients, and synovial membrane cells were cultured under conditions either of hypoxia (1% oxygen) or normoxia (21% ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.1MB, Terms of use)
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- Publisher copy:
- 10.1186/ar2689
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Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- Arthritis research and therapy More from this journal
- Volume:
- 11
- Issue:
- 3
- Pages:
- R64
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
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1478-6362
- ISSN:
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1478-6354
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:25dde704-977f-454d-8d0a-8b6d66bdb737
- Local pid:
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pubs:230626
- Source identifiers:
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230626
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Akhavani et al
- Copyright date:
- 2009
- Notes:
- © 2009 Akhavani et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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