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Ventilatory response to an inhaled constant CO2 load and added dead space in healthy men, awake and asleep.

Abstract:

Experiments were conducted in ten adult men to determine if rapid-eye-movement sleep (REMS) reduced the ventilatory response to two 'steady-state' respiratory loads compared to slow wave sleep (SWS). A constant addition of 150 (or 200) ml/min pure CO2 to the inspirate (7 subjects) and 230 ml of added dead space (5 subjects) were the two respiratory loads. Inspiratory ventilation was measured by pneumotachygraph for at least five continuous minutes in wakefulness, SWS and REMS. The increase in...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
Journal:
Respiration physiology
Volume:
75
Issue:
2
Pages:
183-191
Publication date:
1989-02-05
DOI:
ISSN:
0034-5687
URN:
uuid:25c178ce-9eb7-4acd-aeb1-cc278ebc1ebe
Source identifiers:
43226
Local pid:
pubs:43226

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