Journal article
Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study.
- Abstract:
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Background
Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown.
Methods
As part of a prospective observational study, enrolment plasma cell-free hemoglobin (CFH), lipid peroxidation markers (F2-isoprostanes (F2-IsoPs) and isofurans (IsoFs)), red cell deformability, and serum creatinine were quanti...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
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(Preview, Version of record, pdf, 481.0KB, Terms of use)
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- Publisher copy:
- 10.1186/s12879-017-2373-1
Authors
Funding
+ University of British Columbia
More from this funder
Funding agency for:
Plewes, K
Grant:
MerleA.S
e/PfizerFellowshipinInternationalInfectiousDiseases
+ National Foundation for Infectious Diseases
More from this funder
Funding agency for:
Plewes, K
Grant:
MerleA.S
e/PfizerFellowshipinInternationalInfectiousDiseases
+ Infectious Diseases Society of America, Education and Research Foundation
More from this funder
Funding agency for:
Plewes, K
Grant:
MerleA.S
e/PfizerFellowshipinInternationalInfectiousDiseases
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- BMC Infectious Diseases More from this journal
- Volume:
- 17
- Issue:
- 1
- Pages:
- 313
- Publication date:
- 2017-04-01
- Acceptance date:
- 2017-03-30
- DOI:
- ISSN:
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1471-2334
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:692261
- UUID:
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uuid:25a8349f-8f5a-4f65-a25d-2b6a60789f8b
- Local pid:
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pubs:692261
- Source identifiers:
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692261
- Deposit date:
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2017-05-18
Terms of use
- Copyright holder:
- White et al
- Copyright date:
- 2017
- Notes:
- © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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