- Abstract:
-
PURPOSE: MicroRNA (miRNA) expression alterations have been described in cancer. Many cancers are characterized by areas of hypoxia, enhanced hypoxia-inducible factor (HIF) levels, and increased expression of hypoxically regulated genes, all of which correlate with patient outcome. We examined hypoxia-induced miRNA expression changes to identify markers of survival in breast cancer. EXPERIMENTAL DESIGN: We used microarrays to analyze miRNA expression changes induced by hypoxia in MCF7 breast ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1158/1078-0432.ccr-07-1755
-
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- Journal:
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Volume:
- 14
- Issue:
- 5
- Pages:
- 1340-1348
- Publication date:
- 2008-03-05
- DOI:
- EISSN:
-
1557-3265
- ISSN:
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1078-0432
- URN:
-
uuid:25a3ddb1-cf2e-468f-9475-f789c9ada46a
- Source identifiers:
-
71827
- Local pid:
- pubs:71827
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer.
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