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Journal article

hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer.

Abstract:

PURPOSE: MicroRNA (miRNA) expression alterations have been described in cancer. Many cancers are characterized by areas of hypoxia, enhanced hypoxia-inducible factor (HIF) levels, and increased expression of hypoxically regulated genes, all of which correlate with patient outcome. We examined hypoxia-induced miRNA expression changes to identify markers of survival in breast cancer. EXPERIMENTAL DESIGN: We used microarrays to analyze miRNA expression changes induced by hypoxia in MCF7 breast ...

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Publication status:
Published

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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
14
Issue:
5
Pages:
1340-1348
Publication date:
2008-03-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
URN:
uuid:25a3ddb1-cf2e-468f-9475-f789c9ada46a
Source identifiers:
71827
Local pid:
pubs:71827

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