Journal article icon

Journal article

A note on the power to detect transmission distortion in parent-child trios via the transmission disequilibrium test.

Abstract:

Transmission distortion refers to deviation from the normal 50:50 transmission of alleles from parents to offspring. Identification of genomic regions which undergo distortion is necessary for the correct interpretation of linkage and association studies, since tests of linkage using affected relative pairs and family based tests of association will yield spurious results in the presence of transmission distortion. With the increasing availability of genome-wide high density SNP data (e.g. fr...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s10519-006-9087-2

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Behavior genetics
Volume:
36
Issue:
6
Pages:
947-950
Publication date:
2006-11-05
DOI:
EISSN:
1573-3297
ISSN:
0001-8244
URN:
uuid:2597d74e-6ac6-402b-ac23-acb2787cbbbb
Source identifiers:
33521
Local pid:
pubs:33521

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP