- Abstract:
-
Transmission distortion refers to deviation from the normal 50:50 transmission of alleles from parents to offspring. Identification of genomic regions which undergo distortion is necessary for the correct interpretation of linkage and association studies, since tests of linkage using affected relative pairs and family based tests of association will yield spurious results in the presence of transmission distortion. With the increasing availability of genome-wide high density SNP data (e.g. fr...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s10519-006-9087-2
-
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- Journal:
- Behavior genetics
- Volume:
- 36
- Issue:
- 6
- Pages:
- 947-950
- Publication date:
- 2006-11-05
- DOI:
- EISSN:
-
1573-3297
- ISSN:
-
0001-8244
- URN:
-
uuid:2597d74e-6ac6-402b-ac23-acb2787cbbbb
- Source identifiers:
-
33521
- Local pid:
- pubs:33521
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
A note on the power to detect transmission distortion in parent-child trios via the transmission disequilibrium test.
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