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Hypocapnia alone fails to provoke important electrocardiogram changes in coronary artery diseased patients

Abstract:

Background: There is still an urgent clinical need to develop non-invasive diagnostic tests for early ischemic heart disease because, once angina occurs, it is too late. Hypocapnia has long been known to cause coronary artery vasoconstriction. Some new cardiology tests are accompanied by the claim that they must have potential diagnostic value if hypocapnia enhances their cardiac effects in healthy subjects. But no previous study has tested whether hypocapnia produces bigg...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fphys.2019.01515

Authors


Parkes, MJ More by this author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
ORCID:
0000-0002-4461-8756
Ranasinghe, AM More by this author
Senanayake, E More by this author
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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Physiology Journal website
Volume:
10
Article number:
1515
Publication date:
2020-01-20
Acceptance date:
2019-12-02
DOI:
EISSN:
1664-042X
Pmid:
32038268
Pubs id:
1086051
Local pid:
pubs:1086051

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