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Journal article

Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.

Abstract:

BACKGROUND AND PURPOSE: For patients diagnosed with advanced renal cell carcinoma (RCC), there are few therapeutic options. Radiation therapy is predominantly used to treat metastasis and has not proven effective in the adjuvant setting for renal cancer. Furthermore, RCC is resistant to standard cytotoxic chemotherapies. Targeted anti-angiogenics are the standard of care for RCC but are not curative. Newer agents, such as mTOR inhibitors and others that induce autophagy, have shown great pro...

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Publication status:
Published

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Authors


Anbalagan, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Ferguson, DJ More by this author
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Journal:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Volume:
103
Issue:
3
Pages:
388-393
Publication date:
2012-06-05
DOI:
EISSN:
1879-0887
ISSN:
0167-8140
URN:
uuid:2556ed50-fef1-4a17-8816-ad474f3e4a51
Source identifiers:
329056
Local pid:
pubs:329056

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