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Journal article

Cross-reactive and cross-neutralizing activity of human mumps antibodies against a novel mumps virus from bats.

Abstract:

To evaluate the antigenic relationship between bat mumps virus (BMV) and the JL5 vaccine strain of mumps virus (MuV(JL5)), we rescued a chimeric virus bearing the F and HN glycoproteins of BMV in the genomic background of MuV(JL5) Cross-reactivity and cross-neutralization between this chimeric rMuV(JL5)-F/HN(BMV) virus and rMuV(JL5) were demonstrated using hyperimmune mouse sera and a curated panel of human sera. All mouse and human sera that were able to neutralize rMuV(JL5) infection had cr...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Files:
Publisher copy:
10.1093/infdis/jiw534

Authors


Nachbagauer, R More by this author
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Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Infectious Diseases Journal website
Volume:
215
Issue:
2
Pages:
209-213
Publication date:
2016-11-05
Acceptance date:
2016-10-28
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pubs id:
pubs:657408
URN:
uri:25528a22-e4fe-44c0-9698-570b6a25b8a0
UUID:
uuid:25528a22-e4fe-44c0-9698-570b6a25b8a0
Local pid:
pubs:657408

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