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A few-polyhedra mutant and wild-type nucleopolyhedrovirus remain as a stable polymorphism during serial coinfection in Trichoplusia ni.

Abstract:

Few-polyhedra (FP) mutants of nucleopolyhedroviruses (NPVs) are a well-known phenomenon during serial passage of virus in cell culture. Under these circumstances such mutants produce low yields of occlusion bodies (OBs) and poorly occlude virions, but they are selected for through advantageous rates of budded virus replication. Spontaneous insertion of transposable elements originating from host cell DNA into the viral fp25 gene has been shown to be a common cause of the phenotype. A model of...

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Publication status:
Published

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Authors


Godfray, HC More by this author
O'Reilly, DR More by this author
Journal:
Applied and environmental microbiology
Volume:
69
Issue:
4
Pages:
2052-2057
Publication date:
2003-04-05
DOI:
EISSN:
1098-5336
ISSN:
0099-2240
URN:
uuid:254fcba3-b918-497e-9711-5cf0b9c01f1a
Source identifiers:
210646
Local pid:
pubs:210646

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