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A Hippo in the ointment: MST signalling beyond the fly.

Abstract:

The regulation of cell cycle and apoptosis is fundamental to the control of cell growth and organism homeostasis. Failure to efficiently regulate these processes often results in the increased cell growth observed in tumours. Accumulation of genetic lesions frequently eliminates these regulatory steps so it is imperative that multiple signalling pathways are employed to ensure that efficient control is maintained. Over the last few years a novel signalling pathway entered the limelight that p...

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Publication status:
Published

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Publisher copy:
10.4161/cc.7.7.5630

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Cell cycle (Georgetown, Tex.)
Volume:
7
Issue:
7
Pages:
879-884
Publication date:
2008-04-05
DOI:
EISSN:
1551-4005
ISSN:
1538-4101
URN:
uuid:254cb938-f5af-41ce-8d0f-55780992a4d6
Source identifiers:
131235
Local pid:
pubs:131235

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