Journal article icon

Journal article

Molecular mechanism of sequence-directed DNA loading and translocation by FtsK.

Abstract:

Dimeric circular chromosomes, formed by recombination between monomer sisters, cannot be segregated to daughter cells at cell division. XerCD site-specific recombination at the Escherichia coli dif site converts these dimers to monomers in a reaction that requires the DNA translocase FtsK. Short DNA sequences, KOPS (GGGNAGGG), which are polarized toward dif in the chromosome, direct FtsK translocation. FtsK interacts with KOPS through a C-terminal winged helix domain gamma. The crystal struct...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Ellonen, A More by this author
Atkinson, C More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Expand authors...
Journal:
Molecular cell
Volume:
31
Issue:
4
Pages:
498-509
Publication date:
2008-08-05
DOI:
EISSN:
1097-4164
ISSN:
1097-2765
URN:
uuid:2505f9e3-fae9-4e70-8e23-329c975004e2
Source identifiers:
99758
Local pid:
pubs:99758

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP