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Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized controlled trial.

Abstract:

CONTEXT: Malignant pleural effusion causes disabling dyspnea in patients with a short life expectancy. Palliation is achieved by fluid drainage, but the most effective first-line method has not been determined. OBJECTIVE: To determine whether indwelling pleural catheters (IPCs) are more effective than chest tube and talc slurry pleurodesis (talc) at relieving dyspnea. DESIGN: Unblinded randomized controlled trial (Second Therapeutic Intervention in Malignant Effusion Trial [TIME2]) comparing ...

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Publication status:
Published

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Publisher copy:
10.1001/jama.2012.5535

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Journal:
JAMA
Volume:
307
Issue:
22
Pages:
2383-2389
Publication date:
2012-06-05
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
URN:
uuid:24f89a9b-9d7b-476e-a558-125b18a211a8
Source identifiers:
332945
Local pid:
pubs:332945

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