Journal article
Use of a booster dose of capsular group C meningococcal glycoconjugate vaccine to demonstrate immunologic memory in children primed with one or two vaccine doses in infancy
- Abstract:
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Background Use of a polysaccharide vaccine challenge to demonstrate immunologic memory after priming with capsular group C meningococcal conjugate vaccines (MenCC) risks induction of immunologic hyporesponsiveness. For this reason, MenCC vaccines are now used as probes of immunologic memory, however, no studies have demonstrated their ability to distinguish primed from unprimed children. Methods This study was part of a randomised controlled trial investigating the immunogenicity of a booster...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Accepted manuscript, docx, 391.2KB)
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(Accepted manuscript, pdf, 111.5KB)
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(Accepted manuscript, docx, 23.7KB)
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- Publisher copy:
- 10.1016/j.vaccine.2016.10.038
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Authors
Funding
European Society of Paediatric Infectious Diseases
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Vaccine Journal website
- Volume:
- 34
- Issue:
- 50
- Pages:
- 6350-6357
- Publication date:
- 2016-10-28
- Acceptance date:
- 2016-10-18
- DOI:
- EISSN:
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1873-2518
- ISSN:
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0264-410X
- Source identifiers:
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666592
Item Description
- Keywords:
- Pubs id:
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pubs:666592
- UUID:
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uuid:24f10a5a-b54c-4377-9864-79af115923a7
- Local pid:
- pubs:666592
- Deposit date:
- 2016-12-30
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.vaccine.2016.10.038
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