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Journal article

Use of a booster dose of capsular group C meningococcal glycoconjugate vaccine to demonstrate immunologic memory in children primed with one or two vaccine doses in infancy

Abstract:

Background Use of a polysaccharide vaccine challenge to demonstrate immunologic memory after priming with capsular group C meningococcal conjugate vaccines (MenCC) risks induction of immunologic hyporesponsiveness. For this reason, MenCC vaccines are now used as probes of immunologic memory, however, no studies have demonstrated their ability to distinguish primed from unprimed children. Methods This study was part of a randomised controlled trial investigating the immunogenicity of a booster...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.vaccine.2016.10.038

Authors


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Institution:
University of Oxford
Oxford college:
All Souls College
Role:
Author
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European Society of Paediatric Infectious Diseases More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
34
Issue:
50
Pages:
6350-6357
Publication date:
2016-10-28
Acceptance date:
2016-10-18
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Source identifiers:
666592
Keywords:
Pubs id:
pubs:666592
UUID:
uuid:24f10a5a-b54c-4377-9864-79af115923a7
Local pid:
pubs:666592
Deposit date:
2016-12-30

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