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Acute encephalopathy associated with influenza A infection in adults.

Abstract:
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
Publication status:
Published

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Publisher copy:
10.3201/eid1601.090077

Authors


Lindegardh, N More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
Emerging infectious diseases
Volume:
16
Issue:
1
Pages:
139-142
Publication date:
2010-01-05
DOI:
EISSN:
1080-6059
ISSN:
1080-6040
URN:
uuid:24e98e09-3aae-4635-beb1-db3237e99b5c
Source identifiers:
1816
Local pid:
pubs:1816

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