Acute encephalopathy associated with influenza A infection in adults.

Journal article

We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.

Authors: Lee, N; Wong, C; Chan, P; Lindegardh, N; White, N

• Publication status: Published
• Journal: Emerging infectious diseases
• Volume: 16
• Issue: 1
• Pages: 139-142
• Publication date: 2010-01-01
• DOI: 10.3201/eid1601.090077
• EISSN: 1080-6059
• ISSN: 1080-6040
• Language: English
• Keywords: Influenza, Human; Female; Encephalitis, Viral; Male; Aged, 80 and over; Cytokines; Influenza A virus; Aged; Humans