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Operationalisation of the Randomized Embedded Multifactorial Adaptive Platform for COVID-19 trials in a low and lower-middle income critical care learning health system

Abstract:

The Randomized Embedded Multifactorial Adaptive Platform (REMAP-CAP) adapted for COVID-19) trial is a global adaptive platform trial of hospitalised patients with COVID-19. We describe implementation in three countries under the umbrella of the Wellcome supported Low and Middle Income Country (LMIC) critical care network: Collaboration for Research, Implementation and Training in Asia (CCA). The collaboration sought to overcome known barriers to multi centre-clinical trials in resource-limit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.12688/wellcomeopenres.16486.1

Authors


More by this author
Institution:
University of Oxford
Department:
External
Role:
Author
ORCID:
0000-0001-7046-1580
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-5190-2395
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
St Anne's College
Role:
Author
ORCID:
0000-0002-8288-449X
Publisher:
F1000 Research
Journal:
Wellcome Open Research More from this journal
Volume:
6
Article number:
14
Place of publication:
England
Publication date:
2021-01-28
Acceptance date:
2021-02-16
DOI:
EISSN:
2398-502X
Language:
English
Keywords:
Pubs id:
1159697
Local pid:
pubs:1159697
Deposit date:
2021-04-27

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