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Melanesians and Polynesians share a unique alpha-thalassemia mutation.

Abstract:

Several genetic markers that provide information on population migrations and affinities have been detected by studies of proteins and cellular antigens in blood. Analysis of DNA polymorphisms promises to yield many further population markers, and we report here the distribution of a new alpha-globin gene deletion (-alpha 3.7 III) detected by a restriction enzyme mapping. This is found frequently in Melanesians and Polynesians but not in five other populations in which alpha-thalassemia is pr...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute, Biomedical Research Centre
Bowden, DK More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
Oppenheimer, SJ More by this author
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Journal:
American journal of human genetics
Volume:
37
Issue:
3
Pages:
571-580
Publication date:
1985-05-05
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:24e27b1a-15e9-48ab-a41c-5ce186f60322
Source identifiers:
53944
Local pid:
pubs:53944

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