Journal article icon

Journal article

Cavitation-enhanced delivery of macromolecules into an obstructed vessel.

Abstract:

Poor drug penetration through tumor tissue has emerged as a fundamental obstacle to cancer therapy. The aim of this study was to examine the ability of cavitation instigated by high-intensity focused ultrasound (HIFU) to increase convective transport of a model therapeutic in an in vitro tumor model. Cavitation activity was quantified by analyzing passively recorded acoustic emissions, and mass transfer was quantified using post-treatment image analysis of the distribution of a dye-labeled ma...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1121/1.3496388

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Journal:
Journal of the Acoustical Society of America More from this journal
Volume:
128
Issue:
5
Pages:
EL310-EL315
Publication date:
2010-11-01
DOI:
EISSN:
1520-8524
ISSN:
0001-4966
Language:
English
Keywords:
Pubs id:
pubs:103606
UUID:
uuid:24d97afa-366f-4093-896b-1a0a32484ddb
Local pid:
pubs:103606
Source identifiers:
103606
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP