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MicroRNA Target Identification-Experimental Approaches.

Abstract:

MicroRNAs (miRNAs) are small non-coding RNA molecules of 21-23 nucleotides that control gene expression at the post-transcriptional level. They have been shown to play a vital role in a wide variety of biological processes and dysregulated expression of miRNAs is observed in many pathologies. Understanding the mechanism of action and identifying functionally important mRNA targets of a specific miRNA are essential to unravelling its biological function and to assist miRNA-based drug developme...

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Publication status:
Published

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Publisher copy:
10.3390/biology2010189

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Journal:
Biology More from this journal
Volume:
2
Issue:
1
Pages:
189-205
Publication date:
2013-01-25
DOI:
EISSN:
2079-7737
Language:
English
Pubs id:
pubs:466004
UUID:
uuid:24c408d0-6a60-4608-aed4-6ad3b1943e04
Local pid:
pubs:466004
Source identifiers:
466004
Deposit date:
2014-07-11

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