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Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines

Abstract:

Background: Poor reporting compromises the reliability and clinical value of prognostic tumour marker studies. We review articles to assess the reporting of patients and events using REMARK guidelines, at the time of guideline publication. Methods: We sampled 50 prognostic tumour marker studies from higher impact cancer journals between 2006 and 2007. The inclusion criteria were cancer; focus on single biological tumour marker; survival analysis; multivariable analysis; and not gene array or ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/sj.bjc.6605462

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Institution:
Institute of Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, München, Germany
Role:
Author
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Institution:
Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author

Contributors

Institution:
University of Oxford
Role:
Other
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Funding agency for:
Mallett, S
Altman, D
Publisher:
Nature Publishing Group Publisher's website
Journal:
British Journal of Cancer Journal website
Volume:
102
Issue:
1
Pages:
173-180
Publication date:
2010-01-01
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
Language:
English
Keywords:
Subjects:
UUID:
uuid:24c0d5dc-4c26-43b9-8f6e-90b4f4fc93e5
Local pid:
ora:4860
Deposit date:
2011-01-27

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