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Diastereodivergent organocatalytic asymmetric vinylogous Michael reactions

Abstract:

One of the major challenges of modern asymmetric catalysis is the ability to selectively control the formation of all diastereoisomers of reaction products possessing multiple stereocenters. Pioneers of such diastereodivergent catalytic asymmetric processes have focused on reactions where the newly formed stereogenic centres are proximal to the active carbonyl group. To date, however, diastereodivergent reactions at remote positions remain an unmet challenge. Herein, we describe a catalyst-co...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1038/ncomms5479

Authors


Publisher:
Springer Nature Publisher's website
Journal:
Nature Communications Journal website
Volume:
5
Article number:
4479
Publication date:
2014-07-24
Acceptance date:
2014-06-23
DOI:
EISSN:
2041-1723
Language:
English
Keywords:
UUID:
uuid:24b96aa6-8ee0-435d-a9ce-c3638b9a6466
Local pid:
pubs:477342
Source identifiers:
477342
Deposit date:
2014-09-11

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