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Human genetic susceptibility to infectious disease

Abstract:

Recent genome-wide studies have reported novel associations between common polymorphisms and susceptibility to many major infectious diseases in humans. In parallel, an increasing number of rare mutations underlying susceptibility to specific phenotypes of infectious disease have been described. Together, these developments have highlighted a key role for host genetic variation in determining the susceptibility to infectious disease. They have also provided insights into the genetic architect...

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Publisher copy:
10.1038/nrg3114
Journal:
Nature Reviews Genetics More from this journal
Volume:
13
Issue:
3
Pages:
175-188
Publication date:
2012-03-01
DOI:
EISSN:
1471-0064
ISSN:
1471-0056
Language:
English
Pubs id:
pubs:316835
UUID:
uuid:249f0b7e-bd9d-40be-b51c-bac9a16d3507
Local pid:
pubs:316835
Source identifiers:
316835
Deposit date:
2012-12-19

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