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Journal article

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.

Abstract:

Genome-wide association studies (GWAS) conducted using commercial single nucleotide polymorphisms (SNP) arrays have proven to be a powerful tool for the detection of common disease susceptibility variants. However, their utility for the detection of lower frequency variants is yet to be practically investigated. Here we describe the application of a rare variant collapsing method to a large genome-wide SNP dataset, the Wellcome Trust Case Control Consortium rheumatoid arthritis (RA) GWAS. We ...

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Publication status:
Published

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Publisher copy:
10.1007/s00439-010-0889-1

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Journal:
Human genetics
Volume:
128
Issue:
6
Pages:
627-633
Publication date:
2010-12-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:249a057b-d826-4e92-a48d-ded37abf7ded
Source identifiers:
103726
Local pid:
pubs:103726

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