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Journal article

The over-expression of cell migratory genes in alveolar rhabdomyosarcoma could contribute to metastatic spread

Abstract:

Alveolar (ARMS) and Embryonal (ERMS) rhabdomyosarcoma differ in their response to current treatments. The ARMS subtype has a less favourable prognosis and often presents with widespread metastases, while the less metastatic ERMS has a 5 year survival rate of more than 80 %. In this study we investigate gene expression differences that could contribute to the high frequency of metastasis in ARMS. Microarray analysis identified significant differences in DNA repair, cell cycle and cell migratio...

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Publisher copy:
10.1007/s10585-012-9460-x

Authors


Journal:
Clinical and Experimental Metastasis
Volume:
29
Issue:
5
Pages:
419-429
Publication date:
2012-06-01
DOI:
EISSN:
1573-7276
ISSN:
0262-0898
Source identifiers:
341619
Language:
English
Keywords:
Pubs id:
pubs:341619
UUID:
uuid:2491cfc1-f2e6-4be4-b4d5-32beb58f914c
Local pid:
pubs:341619
Deposit date:
2012-12-19

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