Thesis icon

Thesis

Innate mucosal responses to airway infection

Abstract:

Non-typeable Haemophilus influenzae (NTHi) is the dominant pathogen in human airways diseases and a driver of neutrophilic asthma, while rhinoviruses (RV) serve as the principal triggers of acute exacerbations. Clinical data suggest complex interactions between these two pathogens in the airway mucosa. To investigate this interplay, I established an in vitro model with BEAS-2B cells infected sequentially with NTHi followed by RV. Long-term azithromycin (AZM) treatment red...

Expand abstract

Actions

  • Cite

  • Print

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Oxford college:
St Edmund Hall
Role:
Author
ORCID:
0000-0002-0486-6990

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Research group:
Respiratory Medicine Unit
Oxford college:
New College
Role:
Supervisor
ORCID:
https://orcid.org/0000-0003-0699-2373
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CM CMD
Research group:
Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit
Oxford college:
Green Templeton College
Role:
Supervisor
ORCID:
https://orcid.org/0000-0003-4307-9161

More from this funder
Funder identifier:
https://ror.org/029chgv08
Funding agency for:
Hinks, T
Grant:
104553/z/14/z, 211050/Z/18/z
More from this funder
Funding agency for:
Long, Y
Grant:
2018-I2M-2-002
Programme:
Chinese Scholarship Council (CSC) and the Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Science (CIFMS)

DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
Subjects:
Deposit date:
2025-04-28

Terms of use

Views and Downloads





If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP