Designing recombinant vaccines with viral properties: a rational approach to more effective vaccines.

Journal article

One of the great demands and challenges for vaccination is to successfully target the pathogens responsible for much of mankind's chronic disease burden including: AIDS, infectious hepatitis, tuberculosis and malaria. Another is realizing the potential of therapeutic immunization to cure diseases such as cancer, allergy and inflammatory autoimmunity. To achieve these objectives, the fundamental insights gained from immunology, genomics, molecular-cellular biology and vaccinology must be imple...

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Authors: Jennings, G; Bachmann, M

• Publication status: Published
• Journal: Current molecular medicine
• Volume: 7
• Issue: 2
• Pages: 143-155
• Publication date: 2007-03-01
• DOI: 10.2174/156652407780059140
• EISSN: 1875-5666
• ISSN: 1566-5240
• Language: English
• Keywords: Vaccines, Synthetic; Toll-Like Receptors; Viruses; Humans; B-Lymphocytes; Viral Vaccines; Animals; Antigens, Viral; Immunity, Innate; Ligands; Adjuvants, Immunologic; Antigen-Presenting Cells; Drug Design