- Abstract:
-
This work examines a 1D individual-based model (IBM) for a system of tightly adherent cells, such as an epithelial monolayer. Each cell occupies a bounded region, defined by the location of its endpoints, has both elastic and viscous mechanical properties and is subject to drag generated by adhesion to the substrate. Differential-algebraic equations governing the evolution of the system are obtained from energy considerations. This IBM is then approximated by continuum models (systems of part...
Expand abstract - Publisher copy:
- 10.1093/imammb/dqp015
-
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- Journal:
- Mathematical Medicine and Biology
- Volume:
- 27
- Issue:
- 1
- Pages:
- 39-74
- Publication date:
- 2009-07-17
- DOI:
- EISSN:
-
1477-8602
- ISSN:
-
1477-8599
- URN:
-
uuid:2470e708-8cef-4a05-932d-47d5cdbc4301
- Source identifiers:
-
319119
- Local pid:
- pubs:319119
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Continuum approximations of individual-based models for epithelial monolayers
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