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Intratumoural lymphatics in benign and malignant soft tissue tumours.

Abstract:

Soft tissue sarcomas do not generally metastasise via lymphatics, and the presence or absence of lymphatic vessels within sarcomas and benign soft tissue tumours is not known. In this study, we determined whether lymphatic vessels were present in a wide range of benign and malignant soft tissue lesions by examining intratumoural expression of the lymphatic endothelial cell markers, Lyve-1 and podoplanin. Intratumoural Lyve-1+/podoplanin+ lymphatics were not identified in sarcomas apart from a...

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Publication status:
Published

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Publisher copy:
10.1007/s00428-008-0660-3

Authors


Mahendra, G More by this author
Kliskey, K More by this author
Williams, K More by this author
Hollowood, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
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Journal:
Virchows Archiv : an international journal of pathology
Volume:
453
Issue:
5
Pages:
457-464
Publication date:
2008-11-05
DOI:
EISSN:
1432-2307
ISSN:
0945-6317
URN:
uuid:246d5553-c8e9-4dca-b694-3cfcffe09fed
Source identifiers:
102410
Local pid:
pubs:102410

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