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Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing.

Abstract:

There are limited data on Enterobacter cloacae outbreaks and fewer describing these in association with NDM-1. With whole-genome sequencing, we tested the hypothesis that a cluster of 16 E. cloacae bacteraemia cases in a Nepali neonatal unit represented a single clonal outbreak, using a wider set of epidemiologically unrelated clinical E. cloacae isolates for comparison.Forty-three isolates were analysed, including 23 E. cloacae and 3 Citrobacter sp. isolates obtained from blood cultures from...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/jac/dku521

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Name:
Wellcome Trust
Grant:
HICF-T5-358
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Name:
Department of Health
Grant:
HICF-T5-358
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
More from this funder
Name:
National Institute for Health Research Oxford Biomedical Research Centre
Publisher:
Oxford University Press
Journal:
Journal of antimicrobial chemotherapy More from this journal
Volume:
70
Issue:
4
Pages:
1008-1015
Publication date:
2015-04-01
DOI:
EISSN:
1460-2091
ISSN:
0305-7453

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