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Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing.

Abstract:

There are limited data on Enterobacter cloacae outbreaks and fewer describing these in association with NDM-1. With whole-genome sequencing, we tested the hypothesis that a cluster of 16 E. cloacae bacteraemia cases in a Nepali neonatal unit represented a single clonal outbreak, using a wider set of epidemiologically unrelated clinical E. cloacae isolates for comparison.Forty-three isolates were analysed, including 23 E. cloacae and 3 Citrobacter sp. isolates obtained from blood cultures from...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/jac/dku521

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
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National Institute for Health Research Oxford Biomedical Research Centre More from this funder
Medical Research Council More from this funder
Biotechnology and Biological Sciences Research Council More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
The Journal of antimicrobial chemotherapy Journal website
Volume:
70
Issue:
4
Pages:
1008-1015
Publication date:
2015-04-05
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
URN:
uuid:246a9cbd-433c-4f66-9af5-fe73e10a8436
Source identifiers:
503084
Local pid:
pubs:503084

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