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Journal article

Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.

Abstract:

Stable isotope kinetic studies play an important role in the study of very-low density lipoprotein (VLDL) metabolism, including basic and clinical research. Today, [1,1,2,3,3-(2)H(5)]glycerol is the most cost-effective alternative to measure glycerol and triglyceride kinetics. Recycling of glycerol from glycolysis and gluconeogenesis may lead to incompletely labelled tracer molecules. Many existing methods for the measurement of glycerol isotopic enrichment involve the production of glycerol ...

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Publication status:
Published

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Publisher copy:
10.1002/rcm.4422

Authors


Larsson, T More by this author
Taskinen, MR More by this author
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Journal:
Rapid communications in mass spectrometry : RCM
Volume:
24
Issue:
5
Pages:
586-592
Publication date:
2010-03-05
DOI:
EISSN:
1097-0231
ISSN:
0951-4198
URN:
uuid:24689b08-20d6-403e-97ac-aa43aea34d1e
Source identifiers:
74077
Local pid:
pubs:74077

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