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Detection of BK virus in urine from renal transplant subjects by mass spectrometry.

Abstract:

BACKGROUND: The diagnosis and management of BK virus (BKV) reactivation following renal transplantation continues to be a significant clinical problem. Following reactivation of latent virus, impaired cellular immunity enables sustained viral replication to occur in urothelial cells, which potentially leads to the development of BKV-associated nephropathy (BKVAN). Current guidelines recommend regular surveillance for BKV reactivation through the detection of infected urothelial cells in urin...

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Publisher copy:
10.1186/1559-0275-9-4

Authors


Konietzny, R More by this author
Fischer, R More by this author
Ternette, N More by this author
Wright, CA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
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Publisher:
BioMed Central Ltd.
Journal:
Clinical proteomics
Volume:
9
Issue:
1
Pages:
4
Publication date:
2012
DOI:
EISSN:
1559-0275
ISSN:
1542-6416
URN:
uuid:246356ea-3818-477f-810e-ac81c843a2af
Source identifiers:
325580
Local pid:
pubs:325580

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