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Characterization of monoclonal antibodies to Streptococcus mutans antigenic determinants I/II, I, II, and III and their serotype specificities.

Abstract:

Monoclonal antibodies (McAb) were developed to four protein components of Streptococcus mutans serotype c, some of which are significant in the protection against dental caries. The six McAb used in this investigation support the identities of streptococcal antigens (SA) I/II, I, II, and III. The specificities of these antigenic determinants were established both by direct binding and inhibition with the pure SA with a solid-phase radioassay. Whereas conventional antisera to S. mutans serotyp...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Infection and immunity
Volume:
46
Issue:
1
Pages:
168-175
Publication date:
1984-10-01
EISSN:
1098-5522
ISSN:
0019-9567
Source identifiers:
35454
Language:
English
Keywords:
Pubs id:
pubs:35454
UUID:
uuid:2462aae3-2b83-4331-9008-8c2a65ba332f
Local pid:
pubs:35454
Deposit date:
2012-12-20

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