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Journal article

A Ubiquitin-binding domain that binds a structural fold distinct from that of Ubiquitin

Abstract:

Ubiquitylation, the posttranslational linkage of ubiquitin moieties to lysines in target proteins, helps regulate a myriad of biological processes. Ubiquitin, and sometimes ubiquitin-homology domains, are recognized by ubiquitin-binding domains, including CUE domains. CUE domains are thus generally thought to function by mediating interactions with ubiquitylated proteins. The chromatin remodeler, SMARCAD1, interacts with KAP1, a transcriptional corepressor. The SMARCAD1-KAP1 interaction is di...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/j.str.2019.05.003

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Oxford college:
Balliol
Role:
Author
ORCID:
0000-0001-9365-6487
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Publisher:
Elsevier Publisher's website
Journal:
Structure Journal website
Volume:
27
Issue:
8
Pages:
1316-1325.e6
Publication date:
2019-06-13
Acceptance date:
2019-05-13
DOI:
ISSN:
1878-4186 and 0969-2126
Pubs id:
pubs:1022843
URN:
uri:245828bb-1421-45a7-ad70-8f9c80230945
UUID:
uuid:245828bb-1421-45a7-ad70-8f9c80230945
Local pid:
pubs:1022843

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