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Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations

Abstract:

Parkinson's psychosis (PDP) describes a spectrum of symptoms that may arise in Parkinson's disease (PD) including visual hallucinations (VH). Imaging studies investigating the neural correlates of PDP have been inconsistent in their findings, due to differences in study design and limitations of scale. Here we use empirical Bayes harmonisation to pool together structural imaging data from multiple research groups into a large-scale mega-analysis, allowing us to identify cortical regions and n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-022-28087-0

Authors


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Role:
Author
ORCID:
0000-0002-7542-3089
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Role:
Author
ORCID:
0000-0002-4214-9642
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Name:
Parkinson's UK
Grant:
J-2101
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Name:
Medical Research Council
Grant:
MR/M024962/1
MC_EX_MR/N50192X/1
Publisher:
Springer Nature
Journal:
Nature Communications More from this journal
Volume:
13
Issue:
1
Article number:
519
Place of publication:
England
Publication date:
2022-01-26
Acceptance date:
2021-12-14
DOI:
EISSN:
2041-1723
Pmid:
35082285
Language:
English
Keywords:
Pubs id:
1236442
Local pid:
pubs:1236442
Deposit date:
2022-11-30

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