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Positive and negative elements regulate a melanocyte-specific promoter.

Abstract:

Melanocytes are specialized cells residing in the hair follicles, the eye, and the basal layer of the human epidermis whose primary function is the production of the pigment melanin, giving rise to skin, hair, and eye color. Melanogenesis, a process unique to melanocytes that involves the processing of tyrosine by a number of melanocyte-specific enzymes, including tyrosinase and tyrosinase-related protein 1 (TRP-1), occurs only after differentiation from the melanocyte precursor, the melanobl...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
Journal:
Molecular and cellular biology More from this journal
Volume:
12
Issue:
8
Pages:
3653-3662
Publication date:
1992-08-01
EISSN:
1098-5549
ISSN:
0270-7306

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