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Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation.

Abstract:

Pancreas oxygenation by means of the hyperoxygen carrier perfluorodecalin (PFD) has been established to prevent ischemically induced damage from cold-stored pancreata. However, large-scale studies did not confirm the promising results that had been observed in smaller donor populations. This study assessed whether islet isolation from pancreata stored for prolonged periods can be improved by utilizing the new oxygen carrier perfluorohexyloctane (F6H8) characterized by lower gravity and higher...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Transplant international : official journal of the European Society for Organ Transplantation
Volume:
22
Issue:
10
Pages:
1017-1022
Publication date:
2009-10-05
DOI:
EISSN:
1432-2277
ISSN:
0934-0874
URN:
uuid:244f874f-d4c3-4757-b4f0-1b20848de64d
Source identifiers:
260806
Local pid:
pubs:260806

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