Journal article
The population dynamics of haemoglobins A, A2, F and S in the context of the haemoglobinopathies HbS and α+thalassaemia in Kenyan infants
- Abstract:
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Few studies have described the dynamics of haemoglobin production in African populations with a high prevalence of haemoglobinopathies. We have used the BioRad Variant ClassicTM HPLC method to document the production patterns of the common haemoglobin variants HbA, HbA2, HbF and HbS, stratified by a+thalassaemia genotype, among 15,301 infants recruited to a study on the Coast of Kenya. Notably, we confirm that HbA2 measurements determined using this instrument are unreliable in HbAS and HbSS ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 380.7KB)
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- Publisher copy:
- 10.3324/haematol.2018.199596
Authors
Bibliographic Details
- Publisher:
- Ferrata Storti Foundation Publisher's website
- Journal:
- Haematologica Journal website
- Volume:
- 104
- Pages:
- e184-e186
- Publication date:
- 2018-11-22
- Acceptance date:
- 2018-11-16
- DOI:
- EISSN:
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1592-8721
- ISSN:
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0390-6078
- Pmid:
-
30467202
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:949030
- UUID:
-
uuid:244f456d-6658-4d4d-b833-0accabf66da5
- Local pid:
- pubs:949030
- Source identifiers:
-
949030
- Deposit date:
- 2019-03-11
Terms of use
- Copyright holder:
- Ferrata Storti Foundation
- Copyright date:
- 2018
- Notes:
- © 2019 Ferrata Storti Foundation. This is the publisher's version of the article. The final version is available online from Ferrata Storti Foundation at: https://doi.org/10.3324/haematol.2018.199596
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