Journal article icon

Journal article

The population dynamics of haemoglobins A, A2, F and S in the context of the haemoglobinopathies HbS and α+thalassaemia in Kenyan infants

Abstract:

Few studies have described the dynamics of haemoglobin production in African populations with a high prevalence of haemoglobinopathies. We have used the BioRad Variant ClassicTM HPLC method to document the production patterns of the common haemoglobin variants HbA, HbA2, HbF and HbS, stratified by a+thalassaemia genotype, among 15,301 infants recruited to a study on the Coast of Kenya. Notably, we confirm that HbA2 measurements determined using this instrument are unreliable in HbAS and HbSS ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3324/haematol.2018.199596

Authors


Publisher:
Ferrata Storti Foundation
Journal:
Haematologica More from this journal
Volume:
104
Pages:
e184-e186
Publication date:
2018-11-22
Acceptance date:
2018-11-16
DOI:
EISSN:
1592-8721
ISSN:
0390-6078
Pmid:
30467202
Language:
English
Keywords:
Pubs id:
pubs:949030
UUID:
uuid:244f456d-6658-4d4d-b833-0accabf66da5
Local pid:
pubs:949030
Source identifiers:
949030
Deposit date:
2019-03-11

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP